Project Category: Nature biomedical engineering

April 27, 2023

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Screening hydrogels for antifibrotic properties by implanting cellularly barcoded alginates in mice and a non-human primate

Screening implantable biomaterials for antifibrotic properties is constrained by the need for in vivo testing.

January 31, 2022

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Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics

Circulating cfDNA in cancer patients carries tumor-derived sequences serving as biomarkers for therapy guidance, resistance monitoring, and early cancer detection.

July 1, 2021

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Highly multiplexed rapid DNA detection with single-nucleotide specificity via convective PCR in a portable device

Portable battery-powered PCR enables rapid multiplex DNA quantification.

May 3, 2021

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Selective multiplexed enrichment for the detection and quantitation of low-fraction DNA variants via low-depth sequencing

Blocker-assisted PCR enables low-depth NGS detection of rare DNA variants.

September 4, 2017

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Multiplexed enrichment of rare DNA variants via sequence-selective and temperature-robust amplification

BDA selectively amplifies rare DNA-sequence variants 1,000-fold for easy detection.